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Adenomyosis Explained: Understanding Symptoms, Diagnosis, and Care

Learn what adenomyosis is, association with endometriosis, how it's diagnosed, differences from endometriosis, and treatment and fertility options.

A woman standing in front of a white backdrop holding a cutout of a uterus in front of her pelvis.

This series demystifies adenomyosis for patients newly diagnosed or hearing the word for the first time. We’ll clarify what adenomyosis really is, why it’s often missed, and how it’s different from conditions like endometriosis. Each post covers the journey from symptoms and diagnosis to the full range of treatment options, including effects on fertility. Our goal is to empower you with reliable, patient-focused information and help you advocate for your best care.

Posts in This Series (1)

1

What Adenomyosis Is—and Why Is It Missed?

A flat vector illustration shows a misty forest with layered trees, a winding path, and a magnifying glass revealing hidden roots, symbolizing the elusive nature of adenomyosis diagnosis.

Adenomyosis happens when tissue similar to the uterine lining grows into the uterine muscle (myometrium). It behaves like a whole-uterus condition, driven by estrogen and inflammation, and often involves “progesterone resistance,” which can make symptoms persistent and management more long-term.


Pain can come from real changes in uterine muscle: increased fibrosis (stiffening) and signaling that promotes stronger contractions, alongside reduced pathways that help the muscle relax. Symptoms can be significant even when imaging findings look subtle, and adenomyosis can overlap with endometriosis—so ongoing pelvic pain, heavy bleeding, or fertility stress deserves a focused evaluation rather than dismissal.

2

Adenomyosis vs. Endometriosis: How They’re Different and Related

Coming Soon

Explore the key differences between adenomyosis and endometriosis, their symptoms, overlap, and treatment options for better fertility outcomes.

3

Diagnosing Adenomyosis: What to Expect from Tests and Imaging

Coming Soon

Discover how adenomyosis is diagnosed through tests like ultrasound and MRI. Learn what to expect and understand your symptoms better.

4

Treating Adenomyosis: From IUDs to Surgery Explained

Coming Soon
5

Adenomyosis and Fertility: What Patients Need to Know

Coming Soon

Explore how adenomyosis affects fertility. Learn about symptoms, research, and treatment options for better reproductive health.

Adenomyosis can shape pain, bleeding, energy, intimacy, and fertility—and it’s often dismissed as “normal.” You deserve care that treats your symptoms as real and your goals as central.


Clarity changes outcomes: a careful evaluation, the right imaging and expertise, and a plan tailored to your life can reduce suffering and protect what matters to you—whether that’s symptom relief, preserving fertility, or both.

Get clarity on adenomyosis—today

If heavy bleeding, pelvic pain, or fatigue has been dismissed or confusing, you’re not alone. We can assess your symptoms with a targeted exam annd/or imaging review, explain how adenomyosis differs from endometriosis, and build a treatment plan that fits your goals—including fertility and reducing pain.

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Have a question?

Dr. Steven Vasilev delivers best-in-class endometriosis guidance and a personalized treatment plan—built on evidence and your unique biology.


Led by Steven Vasilev, MD—an internationally recognized endometriosis specialist & MIGS surgeon—Lotus Endometriosis Institute is virtual-forward, with many patients traveling nationally for care. Clinical evaluation and surgical treatment are provided in California.

Santa Monica, CA

2121 Santa Monica Blvd, Santa Monica, CA 90404

Operating Hours

8:00 am - 5:00 pm
Monday - Friday

Arroyo Grande, CA

154 Traffic Way, Arroyo Grande, CA 93420