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Symptoms

Can endometriosis cause flu-like body aches during a flare?

The short answer

Yes, endometriosis can cause flu-like body aches during flares for some patients. Inflammation and nerve irritation may lead to whole-body achiness, fatigue, and a run-down feeling. These symptoms are not specific to endometriosis, and fever or chills should be taken seriously.

Yes, endometriosis can cause flu-like body aches during flares for some patients. Although endometriosis is often thought of as a pelvic condition, lesions can behave like chronically active wounds that drive inflammation, immune signaling, and nerve irritation. This may show up as whole-body achiness, fatigue, and a run-down feeling along with pelvic pain.

That said, flu-like symptoms aren’t specific to endometriosis, and we take them seriously, especially if you also have fever, chills, new respiratory symptoms, or symptoms that don’t follow your usual cycle pattern. If your aches reliably track with your hormonal cycle or occur alongside your typical endometriosis symptoms (pelvic pain, bowel/bladder pain, deep pain with sex), that pattern can be an important clue.

Our team can help you sort out whether your flu-like flares fit an endometriosis/adenomyosis pattern, whether another condition may be contributing, and which treatment path makes the most sense, including when minimally invasive excision surgery is appropriate for both diagnosis and durable relief. If you’re noticing recurring systemic symptoms during flares, reach out to schedule a consultation so we can review your history and build a plan around your specific symptoms.

Where to go from here

Understand it, compare it with what you're feeling, then talk it through with us.

Step 1 · Understand

Understand the condition

Step 2 · Compare

Symptoms it can relate to

Step 3 · Speak with Us

Flu-Like Aches? We Understand.

Endometriosis can cause whole-body aches and fatigue during flares, making you feel run-down. Our specialists can help identify your symptoms and provide relief tailored to you.

Questions people ask next

All symptoms questions
  • Why do I feel flu-like during my period?

    Feeling flu-like during your period often reflects a surge of inflammation as the uterine lining sheds. Prostaglandins can cause aches, chills, headache and nausea, while endometriosis or adenomyosis can amplify inflammation and pain.

  • What does an endometriosis flare feel like?

    An endometriosis flare typically feels like a noticeable spike in pain, such as deep pelvic cramping, pressure or sharp, stabbing pains. It may also include bloating, low back or leg pain, painful bowel movements or urination, fatigue and nausea.

  • Can endometriosis cause arthritis-like joint pain?

    Yes, endometriosis can be associated with arthritis-like joint pain in some people. Whole-body inflammation may show up as aching or stiffness, but the association does not prove causation, and persistent joint pain deserves evaluation for other conditions.

  • Why do I sweat during an endometriosis flare?

    Sweating during an endometriosis flare is often your body’s stress response to pain and inflammation. Pain can trigger a fight-or-flight response with sweating, chills, and shakiness, while inflammation can also disrupt temperature regulation.

Reach Out

Have a question?

Lotus Endometriosis Institute provides California-based surgical evaluation and advanced excision care for patients with suspected endometriosis, adenomyosis, complex pelvic pain, and related conditions.


Many patients contact us from outside California to learn whether traveling for in-person evaluation and possible surgery may be appropriate.

Call Us

(424) 255-1340

(805) 920-0909

Fax: (805) 935-4338

Santa Monica, CA

2121 Santa Monica Blvd, Santa Monica, CA 90404

Operating Hours

8am - 5pm
Monday - Friday

Arroyo Grande, CA

154 Traffic Way, Arroyo Grande, CA 93420