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Fertility

When should I get a miscarriage workup, and what is typically checked?

The short answer

A workup is often recommended after two consecutive first-trimester miscarriages or any second-trimester loss. Typical checks include the uterine cavity, antiphospholipid antibodies and thyroid function, with genetic testing in some situations.

A recurrent pregnancy loss evaluation is often recommended after two consecutive first-trimester miscarriages, or after any second-trimester loss. After a single early loss, many patients don’t need a full workup right away, but if there are additional risk factors or a complex history, we may recommend evaluating sooner.

A typical workup focuses on the most common, actionable causes. This often includes assessing the uterine cavity for issues such as a septum, fibroids, or polyps; checking labs such as antiphospholipid antibodies and thyroid function; and, in some situations, genetic testing such as parental karyotypes. More extensive clotting (thrombophilia) testing is usually reserved for select cases based on your history, and our team can help tailor an evaluation plan to your specific pattern of loss and symptoms.

Where to go from here

Understand it, compare it with what you're feeling, then talk it through with us.

Step 1 · Understand

Understand the condition

Step 2 · Compare

Symptoms it can relate to

Step 3 · Speak with Us

Concerned About Recurrent Miscarriages?

Our specialists understand how difficult pregnancy loss can be and offer thorough evaluations to identify causes. We focus on actionable factors to help you build a path toward a healthy pregnancy.

Questions people ask next

All fertility questions
  • What tests are done after two miscarriages with endometriosis?

    After two miscarriages with endometriosis, we typically review your history and use pelvic imaging, often ultrasound and, when helpful, MRI. We may also evaluate thyroid function and other hormonal factors, and consider autoimmune overlap when symptoms or history point that way.

  • What should a fertility workup include with endometriosis?

    A fertility workup with endometriosis typically looks at egg supply and pelvic anatomy, with ovarian reserve tests, pelvic ultrasound and commonly a partner's semen analysis. Depending on your history and imaging, it may include tests to see if the fallopian tubes are open, and sometimes MRI.

Reach Out

Have a question?

Lotus Endometriosis Institute provides California-based surgical evaluation and advanced excision care for patients with suspected endometriosis, adenomyosis, complex pelvic pain, and related conditions.


Many patients contact us from outside California to learn whether traveling for in-person evaluation and possible surgery may be appropriate.

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(424) 255-1340

(805) 920-0909

Fax: (805) 935-4338

Santa Monica, CA

2121 Santa Monica Blvd, Santa Monica, CA 90404

Operating Hours

8am - 5pm
Monday - Friday

Arroyo Grande, CA

154 Traffic Way, Arroyo Grande, CA 93420